Temporarily, the International Warehouse 2 can ship to USA ONLY. DO NOT PLACE ORDERS IF YOU ARE BASED IN OTHER COUNTRY!
Thank you for understanding,
OSGear Team
Aranesp 20 mcg - Amgen
CLASSIFICATION Glycoprotein Cytokine
ACNE No
WATER RETENTION No
HBR No
HEPATOTOXICITY No
AROMATIZATION No
MANUFACTURER Amgen
WAREHOUSE International Warehouse 2
SUBSTANCE
Erythropoietin,
Aranesp 20 mcg
Pharmacological action - hematopoietic.
Pharmacodynamics
Darbepoetin alfa stimulates erythropoiesis by the same mechanism as endogenous erythropoietin. Darbepoetin alfa contains 5 N-linked carbohydrate chains, while endogenous hormone and recombinant human erythropoietin (rhEPO) have only three chains. Additional sugar residues, from a molecular point of view, do not differ from those present in the endogenous hormone. Due to the increased content of carbohydrates, darbepoetin alfa has a longer half-life in comparison with rhEPO, and, consequently, greater activity in vivo. Despite these changes in molecular structure, darbepoetin alfa retains a very narrow specificity for the erythropoietin receptor.
Erythropoietin is a growth factor that mainly stimulates the production of red blood cells. Erythropoietin receptors can be expressed on the surface of various tumor cells.
